If you’re a fan of creamy, cheesy comfort food, you’re going to absolutely love this Chicken Alfredo Lasagna Recipe. It’s the perfect crossover between rich Alfredo sauce and classic lasagna layers, loaded with tender chicken and fresh spinach. When I first tried this, it quickly became a go-to for family dinners because it’s just so satisfying and downright delicious. Stick with me, and I’ll walk you through every step to make it turn out perfectly every time.

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Why You’ll Love This Recipe

Comfort Food Upgrade: It combines creamy Alfredo sauce with lasagna layers, making it more indulgent than your everyday lasagna.
Family-Friendly: My family goes crazy for this—it’s crowd-pleasing even for picky eaters.
Simple Ingredients: No fancy or hard-to-find ingredients, just pantry staples with a few fresh add-ins.
Versatile: You can easily swap or add veggies to customize it your way.

The image shows a white baking dish filled with a lasagna that has four visible layers. The top layer is golden brown, bubbly melted cheese with some darker brown spots and a few green basil leaves scattered on top. Underneath is a thick white sauce layer dotted with fresh spinach leaves adding green color. Below, there is a creamy chicken and cheese mixture layer with a soft, smooth texture, and at the bottom, a slightly browned sauce-covered pasta layer is visible. A golden spatula is lifting one piece, showing the layers clearly and the melted cheese stretching slightly. The dish is placed on a white marbled surface. Photo taken with an iphone --ar 4:5 --v 7

Ingredients You’ll Need

Each ingredient plays an essential role—creamy cheeses bring richness, spinach adds freshness and color, and the chicken packs a hearty protein punch. Here’s what I recommend grabbing, along with a few handy tips.

Olive oil: Use a good-quality extra virgin olive oil for sautéing the spinach for subtle flavor.
Spinach: Fresh spinach works best for the bright green color and texture; avoid frozen here.
Butter: Essential for that luscious Alfredo base; salted or unsalted both work, just adjust seasoning.
All-purpose flour: This acts as the thickening agent for your sauce; whisk well to avoid lumps.
Whole milk: I like whole milk for richness, but you can try 2% if you prefer it lighter.
Ground nutmeg: Just a pinch adds a lovely warmth and depth to the Alfredo sauce—don’t skip this!
Parmesan cheese: Freshly grated Parmesan makes a huge difference for flavor.
Ricotta cheese: Adds creamy texture between pasta layers; make sure it’s well drained if unusually watery.
Lasagna sheets: No-boil or regular sheets; just adjust cooking time accordingly.
Cooked chicken: Rotisserie chicken is a lifesaver here—but homemade shredded chicken works beautifully too.
Mozzarella cheese: Use good-quality shredded mozzarella for that melt and golden top.

Note: You’ll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Variations

I love how adaptable this Chicken Alfredo Lasagna Recipe is—over time, I’ve played around with it to suit different tastes and dietary needs. Feel free to make it yours with a few simple swaps.

Vegetarian Version: Swap chicken for roasted mushrooms or a medley of roasted veggies—trust me, it still hits all the creamy, comforting notes.
Low-Carb Option: Use thinly sliced zucchini or eggplant instead of lasagna noodles; just be sure to dry them well to avoid watery layers.
Spicy Twist: Add crushed red pepper flakes to the Alfredo sauce or layer in some sautéed jalapeños for a little heat.
Dairy-Free: Try a cashew-based Alfredo sauce and dairy-free cheeses to make it allergy-friendly; though the texture will be different, it’s still yummy.

How to Make Chicken Alfredo Lasagna Recipe

Step 1: Wilt the Spinach Just Right

Start by heating olive oil in a skillet over medium heat. Toss in your fresh spinach and sauté just until it wilts—this only takes about 2 minutes, so keep an eye on it! You want it tender but still vibrant green. Once done, set it aside because swapping out soggy spinach for perfectly wilted makes a world of difference.

Step 2: Make That Velvety Alfredo Sauce

Melt the butter in a large saucepan over medium heat, then whisk in the flour to form a roux. This little step is where you build that creamy sauce base. Cook the roux for 1-2 minutes, stirring constantly; don’t let it brown. Slowly whisk in the milk, adding it little by little to avoid lumps. Keep stirring until the sauce thickens—you’ll know it’s ready when it coats the back of a spoon, about 5-7 minutes. Remove from heat, stir in grated Parmesan, a pinch of nutmeg, and season it with salt and pepper. This sauce is the star here, so taste and adjust seasoning if you need to.

Step 3: Prep the Ricotta Cheese

In a small bowl, mix the ricotta cheese with a pinch of salt and pepper. This extra seasoning really helps the ricotta stand out against the rich Alfredo sauce. If your ricotta is watery, give it a little drain in a fine sieve beforehand—too much moisture can make your lasagna runny.

Step 4: Start Layering the Goodness

Grab a deep baking dish and spread a thin layer of Alfredo sauce on the bottom to keep things from sticking. Lay down a layer of lasagna sheets, followed by a third of the ricotta, cooked chicken, wilted spinach, and mozzarella cheese. Top with some Alfredo sauce to keep the layers moist and gooey. Repeat these layers two more times, finishing with a generous layer of mozzarella on top. The layering is key—the balance of cheese, chicken, sauce, and pasta creates that irresistible texture I can’t get enough of.

Step 5: Bake Until Golden and Bubbly

Cover your lasagna tightly with foil—this keeps the moisture in and prevents the cheese from burning. Bake in a preheated oven at 350°F (175°C) for 20 minutes. Then, remove the foil and bake for an additional 10 minutes so the cheese on top turns a beautiful golden brown and bubbles up invitingly. Letting it rest for 15 minutes before serving really helps everything settle and makes slicing cleaner. Trust me, patience here is worth it.

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Pro Tips for Making Chicken Alfredo Lasagna Recipe

Smoothing the Sauce: When adding milk to the roux, pour slowly and whisk constantly to prevent lumps—this saved me many times!
Drain Ricotta Well: Too much moisture here can make the layers watery, so I always give mine a quick drain if needed.
Use Rotisserie Chicken: It’s an easy shortcut that adds flavor and saves cooking time without sacrificing taste.
Rest Before Serving: Letting the lasagna sit after baking makes it easier to cut neat slices and lets flavors meld beautifully.

How to Serve Chicken Alfredo Lasagna Recipe

A piece of lasagna with three visible layers sits on a white plate with a delicate pattern. The bottom layer is creamy white sauce mixed with green spinach, the middle layer shows a light yellow pasta sheet, and the top layer is golden brown melted cheese with a few small fresh green basil leaves on top. The lasagna looks soft and slightly browned in some spots. Black pepper is sprinkled around on the plate, and a silver fork is placed resting near the lasagna. The surface underneath is a white marbled texture. photo taken with an iphone --ar 4:5 --v 7

Garnishes

I keep it simple with a sprinkle of fresh chopped parsley or basil over each slice—it adds a pop of color and fresh herbal brightness that balances the richness. Sometimes a little extra grated Parmesan on top before serving is always a crowd-pleaser too.

Side Dishes

This lasagna is pretty rich, so I like to pair it with light sides like a crisp Caesar or mixed green salad, and some garlic bread to soak up any extra sauce. Roasted or steamed broccoli is another favorite at my house—adds green and crunch.

Creative Ways to Present

For special occasions, I’ve layered this into individual ramekins for single servings, which makes it feel extra fancy and perfect for dinner parties. You can also cut it into neat squares and place on a platter with colorful garnishes for a buffet-style meal that looks as good as it tastes.

Make Ahead and Storage

Storing Leftovers

After the lasagna cools completely, I cover it tightly with plastic wrap or transfer slices into an airtight container. It keeps great in the fridge for up to 4 days. I’ve found that this recipe actually tastes even better the next day as the flavors meld together.

Freezing

I often freeze the whole lasagna before baking, tightly wrapped with foil and plastic wrap to prevent freezer burn. When I’m ready to eat, I thaw overnight in the fridge and then bake as usual. This trick saves so much time on busy days and the texture stays surprisingly good.

Reheating

To reheat leftovers, I cover the slice loosely with foil and warm it in a 350°F oven for about 15-20 minutes, or until heated through. This keeps the cheese melty and prevents it from drying out like a microwave sometimes does.

FAQs

Can I use no-boil lasagna noodles in this Chicken Alfredo Lasagna Recipe?

Absolutely! No-boil noodles work well here and save you time. Just be sure to spread a little extra sauce to ensure they cook properly in the oven and don’t end up dry.
What type of chicken works best for this recipe?

Cooked shredded chicken is perfect—leftover roasted chicken or rotisserie chicken are convenient and flavorful choices that fit right in.
Can I make the Alfredo sauce ahead of time?

Yes, you can prepare the Alfredo sauce a day in advance. Just store it in the fridge and gently reheat it before assembling the lasagna, stirring well to bring back its creamy texture.
How do I prevent the lasagna from being watery?

Make sure to drain the ricotta if it’s watery and don’t over-soak the pasta sheets (especially if using no-boil). Also, sauté the spinach and remove excess moisture to keep your layers firm.
Can I add other vegetables to this Chicken Alfredo Lasagna Recipe?

Definitely! Mushrooms, zucchini, or roasted red peppers are delicious additions. Just sauté any veggies first to reduce moisture before layering.

Final Thoughts

This Chicken Alfredo Lasagna Recipe has become one of my absolute favorites because it’s creamy, flavorful, and reliably hits the spot every time. I love sharing it with friends because it feels so special but is surprisingly easy to make. If you want a comforting, crowd-pleasing meal that’s sure to impress without hours in the kitchen, give this a try—I think you’ll find it as delicious and rewarding as I do!